Drug NameMevacor (Lovastatin)
Drug UsesHigh LDL cholesterol is usually first treated with exercise, weight loss in obese individuals, and a diet low in cholesterol and saturated fats. When these measures fail, cholesterol-lowering medications such as mevacor can be added. The National Cholesterol Education Program (NCEP) has published treatment guidelines for use of these medications. These treatment guidelines take into account the level of LDL cholesterol as well as the presence of other risk factors such as diabetes, hypertension, cigarette smoking, low HDL cholesterol level, and family history of early coronary heart disease. The effectiveness of the medication in lowering cholesterol is dose- related. Blood cholesterol determinations are performed in regular intervals during treatment so that dosage adjustments can be made. A reduction in LDL cholesterol level can be seen two weeks after starting therapy.
How to useMay be taken on an empty or full stomach. The medication seems to be most effective when given with the evening meal.
Drug Class and MechanismMevacor is a cholesterol-lowering medicine. It inhibits the production of cholesterol by the liver. It lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease. Lowering LDL cholesterol levels retards progression and may even reverse coronary artery disease.
Missed DoseIf you miss a dose of this medicine and you are taking 1 dose daily, take the missed dose if you remember the same day. Skip the missed dose if you do not remember until the next day. Do not take 2 doses at once.
StorageTablets should be stored at room temperature in a tightly closed container.
Warnings/PrecautionsDo not take this medicine if you have had an allergic reaction to it or are allergic to any ingredient in this product. Laboratory and/or medical tests, including liver function tests and blood cholesterol levels, may be performed to monitor your progress or to check for side effects. Keep all doctor and laboratory appointments while you are using this medicine. Before having any kind of surgery, tell your doctor that you are taking this medicine. Eating grapefruit or drinking grapefruit juice while you are taking this medicine may increase the amount of this medicine in your blood, which may increase your risk for serious side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet while you are taking this medicine. Before you begin taking any new medicine, either prescription or over-the-counter, check with your doctor or pharmacist. For women: do not use this medicine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. It is recommended that women of childbearing age use effective birth control measures while taking this medicine since lovastatin may cause fetal harm. It is unknown if this medicine is excreted in breast milk. Do not breast-feed while taking this medicine.
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